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IL-10 constrains sphingolipid metabolism via fatty acid desaturation to limit inflammation

2023-05-08

Abstract excerpt

Unchecked chronic inflammation is the underlying cause of many diseases, ranging from inflammatory bowel disease to obesity and neurodegeneration. Given the deleterious nature of unregulated inflammation, it is not surprising that cells have acquired a diverse arsenal of tactics to limit inflammation. IL-10 is a key anti-inflammatory cytokine that can limit immune cell activation and cytokine production in innate...

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Literature Corpus work
3fe9bf94-3025-5b97-bbbc-9443b847ee30
DOI
10.1101/2023.05.07.539780
Open publication

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IL-10 constrains sphingolipid metabolism via fatty acid desaturation to limit inflammationDOI 10.1101/2023.05.07.539780
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