Article
Polygenic signals of sexually antagonistic selection in contemporary human genomes
2021-09-22
Abstract excerpt
Mutations that increase fitness in one sex may decrease fitness in the other. Such “sexually antagonistic” (SA) genetic variants can constrain adaptation and increase variability for fitness components (e.g., survival, fertility, and disease susceptibility). However, detecting SA selection in genomes is immensely challenging, as it requires prohibitively large datasets that combine genomic sequences with individua...
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Identifiers and source
- Literature Corpus work
- 04713fff-7f65-5c3d-a5a3-e1dd0ecdd610
- DOI
- 10.1101/2021.09.20.461171