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Article

An unbiased test reveals no enrichment of sexually antagonistic polymorphisms on the human X chromosome.

Proceedings. Biological sciences - 26 Jan 2022

Ruzicka Filip, Connallon Tim

Abstract excerpt

Mutations with beneficial effects in one sex can have deleterious effects in the other. Such 'sexually antagonistic' (SA) variants contribute to variation in life-history traits and overall fitness, yet their genomic distribution is poorly resolved. Theory predicts that SA variants could be enriched on the X chromosome or autosomes, yet current empirical tests face two formidable challenges: (i) identifying SA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35078366
DOI: 10.1098/rspb.2021.2314
PMCID: PMC8790371

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