Article

Distribution of age at natural menopause, age at menarche, menstrual cycle length, height and BMI in BRCA1 and BRCA2 pathogenic variant carriers and non-carriers: Results from EMBRACE

2025-02-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Carriers of germline pathogenic variants (PVs) in the BRCA1 and BRCA2 genes are at higher risk of developing breast and ovarian cancer than the general population. It is unclear if these PVs influence other breast or ovarian cancer risk factors, including age at menopause (ANM), age at menarche (AAM), menstrual cycle length, BMI or height. There is a biological rationale for a...

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Literature Corpus work: 045d8f01-bd3d-5c98-a633-8a14d072b2c0
DOI: 10.1101/2025.02.12.25321672

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