Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan.

doi:10.1016/j.canep.2013.12.001

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Article

Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan.

Cancer epidemiology - 1 Feb 2014

Warren Andersen Shaneda, Trentham-Dietz Amy, Gangnon Ronald E, Hampton John M, Skinner Halcyon G, Engelman Corinne D, Klein Barbara E, Titus Linda J, Egan Kathleen M, Newcomb Polly A

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with breast cancer risk. Some of these loci have unknown functional significance and may mediate the effects of hormonal exposures on breast cancer risk. We examined relationships between breast cancer susceptibility variants and menstrual/reproductive factors using data from two population-based studies....

Topics

Adult
Aged
Breast Neoplasms
Case-Control Studies
Cohort Studies
Female
Genetic Predisposition to Disease
Humans
Menarche
Menopause

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymorphism, Single Nucleotide

Reproductive History

Risk Factors

United States

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24373701
DOI: 10.1016/j.canep.2013.12.001
PMCID: PMC4023814

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CASP8

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