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Genome-wide polygenic risk score for type 2 diabetes in Indian population.

Scientific reports - 18 Jul 2023

Pemmasani Sandhya Kiran, Atmakuri Shravya, Acharya Anuradha

Abstract excerpt

Genome-wide polygenic risk scores (PRS) for lifestyle disorders, like Type 2 Diabetes (T2D), are useful in identifying at-risk individuals early on in life, and to guide them towards healthier lifestyles. The current study was aimed at developing PRS for the Indian population using imputed genotype data from UK Biobank and testing the developed PRS on data from GenomegaDB of Indians living in India. 959 T2D cases...

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37463971
DOI: 10.1038/s41598-023-38768-5
PMCID: PMC10354074

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