Article

Plasmodium falciparum Kelch13 polymorphisms identified after treatment failure with artemisinin- based combination therapy in Niger

2022-12-21

Abstract excerpt

<h4>Background: </h4> Artemisinin-based combination therapy (ACT) is the most effective treatment for malaria, and has significantly reduced morbimortality. Polymorphisms associated with the Plasmodium falciparum kelch gene ( Pfkelch13 ) propeller domains have been associated with delayed parasite clearance even with ACT treatment. <h4>Methods: </h4>: The Pfkelch13 gene was sequenced from P. falciparum infected p...

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Literature Corpus work: 04341080-2d9a-53ec-acf2-5dfac1409bb1
DOI: 10.21203/rs.3.rs-2390016/v1

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