Article
Molecular assessment of kelch13 non-synonymous mutations in Plasmodium falciparum isolates from Central African Republic (2017-2019).
Malaria journal - 24 May 2020
Nzoumbou-Boko Romaric, Panté-Wockama Chris-Boris Gildas, Ngoagoni Carine, Petiot Nathalie, Legrand Eric, Vickos Ulrich, Gody Jean-Chrysostome, Manirakiza Alexandre, Ndoua Christophe, Lombart Jean-Pierre, Ménard Didier
Abstract excerpt
BACKGROUND: Over the last decade, artemisinin-based combination therapy (ACT) has contributed substantially to the decrease in malaria-related morbidity and mortality. The emergence of Plasmodium falciparum parasites resistant to artemisinin derivatives in Southeast Asia and the risk of their spread or of local emergence in sub-Saharan Africa are a major threat to public health. This study thus set out to...
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