Article
Molecular profiling of the artemisinin resistance Kelch 13 gene in Plasmodium falciparum from Nigeria.
PloS one - 1 Jan 2022
Ajogbasile Fehintola V, Oluniyi Paul E, Kayode Adeyemi T, Akano Kazeem O, Adegboyega Benjamin B, Philip Courage, Ogbulafor Nnenna, Okafor Henrietta U, Oguche Stephen, Wammanda Robinson D, Mokuolu Olugbenga A, Folarin Onikepe A, Happi Christian T
Abstract excerpt
Accurate assessment and monitoring of the Plasmodium falciparum Kelch 13 (pfk13) gene associated with artemisinin resistance is critical to understand the emergence and spread of drug-resistant parasites in malaria-endemic regions. In this study, we evaluated the genomic profile of the pfk13 gene associated with artemisinin resistance in P. falciparum in Nigerian children by targeted sequencing of the pfk13 gene....
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