Article

TMPO promotes cellular dissemination and metastasis in circulating tumor cells

2025-12-27

Abstract excerpt

Metastasis—the process by which cancer cells spread beyond the primary tumor to distant organs—accounts for the vast majority of cancer-related deaths. To elucidate mechanisms underlying dissemination and metastasis in prostate cancer, we have investigated circulating tumor cells (CTCs) obtained from genetically engineered mouse models (GEMMs). The phenotypic and molecular properties of the CTCs, and organoids der...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 041a081f-a329-5875-9d5d-b89d75506a52
DOI: 10.64898/2025.12.27.696673

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TMPO promotes cellular dissemination and metastasis in circulating tumor cellsDOI 10.64898/2025.12.27.696673Read

Distinct mesenchymal cell states mediate prostate cancer progressionSemantic proximity Read

Dissecting the contributions of tumor heterogeneity on metastasis at single-cell resolutionSemantic proximity Read

Multi-omics evaluation of cell lines as models for metastatic prostate cancerSemantic proximity Read

Single-cell proteomics defines the cellular heterogeneity of localized prostate cancerSemantic proximity Read

Generation of prostate cancer assembloids modeling the patient-specific tumor microenvironmentSemantic proximity Read

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolutionSemantic proximity Read

Multi-omics evaluation of cell lines as models for metastatic prostate cancer.Semantic proximity Read

Cells in the Polyaneuploid Cancer Cell State are Pro-MetastaticSemantic proximity Read

Identification of epithelial and mesenchymal circulating tumor cells in clonal lineage of an aggressive prostate cancer caseSemantic proximity Read

Single-cell analysis revealing the metabolic landscape of prostate cancerSemantic proximity Read

Single-Cell Proteomics Defines the Cellular Heterogeneity of Localized Prostate CancerSemantic proximity Read

Distinct mesenchymal cell states mediate prostate cancer progressionSemantic proximity Read