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Article

Single-cell analysis revealing the metabolic landscape of prostate cancer

23 Apr 2024

Abstract excerpt

ABSTRACT: Tumor metabolic reprogramming is a hallmark of cancer development, and targeting metabolic vulnerabilities has been proven to be an effective approach for castration-resistant prostate cancer (CRPC) treatment. Nevertheless, treatment failure inevitably occurs, largely due to cellular heterogeneity, which cannot be deciphered by traditional bulk sequencing techniques. By employing computational pipelines...

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PMID: 38657119
DOI: 10.4103/aja20243

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