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Article

Mutations in the ilvN gene mitigate growth inhibitory effect of cysteine in Corynebacterium glutamicum.

Applied microbiology and biotechnology - 10 Mar 2025

Matsuhisa Kazuho, Ogawa Katsuhiro, Komata Kento, Hirasawa Takashi

Abstract excerpt

Cysteine, a common amino acid used in food, cosmetic, and pharmaceutical industries, has a growth inhibitory effect. This growth inhibition by cysteine poses a problem, as the production of cysteine using microbial cells results in decreased cell growth and cysteine productivity. The underlying mechanism of growth inhibition by cysteine is unclear. This study aims to understand the mechanism of growth inhibition...

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Identifiers

PMID: 40063103
DOI: 10.1007/s00253-025-13444-y
PMCID: PMC11893703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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