Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum.

Applied microbiology and biotechnology - 1 Oct 2006

Hayashi Mikiro, Mizoguchi Hiroshi, Ohnishi Junko, Mitsuhashi Satoshi, Yonetani Yoshiyuki, Hashimoto Shin-ichi, Ikeda Masato

Abstract excerpt

We previously found by transcriptome analysis that global induction of amino acid biosynthetic genes occurs in a classically derived industrial L-lysine producer, Corynebacterium glutamicum B-6. Based on this stringent-like transcriptional profile in strain B-6, we analyzed the relevant mutations from among those identified in the genome of the strain, with special attention to the genes that are involved in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corynebacterium glutamicum
Share to Fermentation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Genetic Engineering

Share to Genome, Bacterial

Share to Industrial Microbiology

Share to Lysine

Share to Transcription, Genetic

Source

Identifiers

PMID: 16944136
DOI: 10.1007/s00253-006-0539-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum.PMID 16944136Read ↗

A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production.Semantic proximity Read ↗

A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum.Semantic proximity Read ↗

Improving lysine production by Corynebacterium glutamicum through DNA microarray-based identification of novel target genes.Semantic proximity Read ↗

A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant.Semantic proximity Read ↗

Analysis of α-isopropylmalate synthase variant and its effect on L-leucine synthesis in Corynebacterium glutamicumSemantic proximity Read ↗

Next-generation sequencing-based genome-wide mutation analysis of L-lysine-producing Corynebacterium glutamicum ATCC 21300 strain.Semantic proximity Read ↗

A novel aceE mutation leading to a better growth profile and a higher L-serine production in a high-yield L-serine-producing Corynebacterium glutamicum strain.Semantic proximity Read ↗

Efficient 40 degrees C fermentation of L-lysine by a new Corynebacterium glutamicum mutant developed by genome breeding.Semantic proximity Read ↗

Complete genome sequence of Corynebacterium glutamicum B253, a Chinese lysine-producing strain.Semantic proximity Read ↗

Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer.Semantic proximity Read ↗

Identification of a suppressor gene for the arginine-auxotrophic argJ mutation in Corynebacterium glutamicum.Semantic proximity Read ↗

Analysis of strain-specific genes in glutamic acid-producing Corynebacterium glutamicum ssp. lactofermentum AJ 1511.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.