Article

BDF6 deficiency severely compromises intracellular amastigote development and infectivity of <i>Trypanosoma cruzi</i>

2025-07-21

Abstract excerpt

Trypanosoma cruzi , the causative agent of Chagas disease, relies on complex gene regulatory mechanisms to adapt to its diverse host environments. In recent years, it has been established that epigenetics plays an essential role in these mechanisms via the regulation of chromatin structure. Bromodomain-containing factors (BDFs), known for recognizing acetylated lysines on histones, have emerged as key factors in c...

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Literature Corpus work: 03d3bd78-125b-5215-bf3c-43674a013185
DOI: 10.1101/2025.07.21.665854

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