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The <i>Trypanosoma cruzi</i> cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiation

2024-10-01

Abstract excerpt

Trypanosoma cruzi , the causative agent of Chagas disease, exhibits a complex life cycle with multiple hosts, stages and differentiation steps. We present a complete cell atlas for the T. cruzi life cycle, based on single cell transcriptomes for over 31,000 cells and population-based transcriptomics. The atlas reveals many life cycle associated genes and can be utilised to accurately annotate life cycle stages. I...

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Literature Corpus work
0767d550-c36f-59f1-a67d-a5df7a78bff1
DOI
10.1101/2024.10.01.616042
Open publication

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