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Transcriptomic analysis of N-terminal mutated <i>Trypanosoma cruzi</i> UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development

2023-12-08

Abstract excerpt

<h4>ABSTRACT</h4> During its life cycle, the human pathogen Trypanosoma cruzi must quickly adapt to different environments, in which the variation in the gene expression of the regulatory U-rich RNA-binding protein 1 (TcUBP1) plays a crucial role. We have previously demonstrated that the overexpression of TcUBP1 in insect-dwelling epimastigotes orchestrates an RNA regulon to promote differentiation to infective f...

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Literature Corpus work
8aece01a-8ce2-53fb-a4bb-bd5e4ea737f4
DOI
10.1101/2023.12.07.570581
Open publication

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Transcriptomic analysis of N-terminal mutated <i>Trypanosoma cruzi</i> UBP1 knockdown underlines the importance of this RNA-binding protein in parasite developmentDOI 10.1101/2023.12.07.570581
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