Article

Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling

2025-09-22

Abstract excerpt

<h4>Summary</h4> Opioids are potent analgesics often prescribed for the treatment of chronic pain, a condition affecting millions worldwide. Although pain states increase vulnerability to opioid use disorders, the neural mechanisms underlying this interaction remain incompletely understood. The ventral tegmental area (VTA) is a key site for opioid actions, and emerging evidence suggests that pain states and opioi...

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Literature Corpus work: 03a1bcd4-4b0f-5b87-98ed-d534c57f0024
DOI: 10.1101/2025.09.22.677814

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