Article

Massively parallel characterization of adolescent idiopathic scoliosis risk variants

2026-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Adolescent idiopathic scoliosis (AIS) is a common pediatric musculoskeletal disorder characterized by lateral spinal curvature, often leading to chronic pain and deformity. While a significant genetic component to AIS is recognized, the functional impact of most associated genetic variants, particularly those in non-coding regions, remains largely unknown. Using massively parallel reporter assay...

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Literature Corpus work: 037e42b6-f295-521b-b075-c3fccce87292
DOI: 10.64898/2026.08.05.743047

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