Article

Genomic characterization of the adolescent idiopathic scoliosis associated transcriptome and regulome

2020-03-04

Abstract excerpt

Adolescent idiopathic scoliosis (AIS), a sideways curvature of the spine, is the most common pediatric musculoskeletal disorder, affecting ∼3% of the population worldwide. However, its genetic bases and tissues of origin remain largely unknown. Several genome-wide association studies (GWAS) have implicated nucleotide variants in noncoding sequences that control genes with important roles in cartilage, muscle, bone...

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Literature Corpus work: 28ec87aa-0b4f-5eda-9f0f-e8b86b73e1b5
DOI: 10.1101/2020.03.02.973735

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