Article

IL-27R signaling serves as immunological checkpoint for NK cells to promote hepatocellular carcinoma

2020-12-29

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common form of liver cancer with poor survival and limited therapeutic options. HCC has different etiologies, typically associated with viral or carcinogenic insults or fatty liver disease and underlying chronic inflammation presents as a major unifying mechanism for tumor promotion. On the other hand, mechanisms of how inflammatory response can regulate anti-cancer immun...

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Literature Corpus work: 035d8daf-6dad-5aeb-8ff1-165e94a5d2ef
DOI: 10.1101/2020.12.28.424635

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