Article
Interleukin 17-producing γδT cells promote hepatic regeneration in mice.
Gastroenterology - 1 Aug 2014
Rao Raghavendra, Graffeo Christopher S, Gulati Rishabh, Jamal Mohsin, Narayan Suchithra, Zambirinis Constantinos P, Barilla Rocky, Deutsch Michael, Greco Stephanie H, Ochi Atsuo, Tomkötter Lena, Blobstein Reuven, Avanzi Antonina, Tippens Daniel M, Gelbstein Yisroel, Van Heerden Eliza, Miller George
Abstract excerpt
BACKGROUND & AIMS: Subsets of leukocytes synergize with regenerative growth factors to promote hepatic regeneration. γδT cells are early responders to inflammation-induced injury in a number of contexts. We investigated the role of γδT cells in hepatic regeneration using mice with disruptions in Tcrd (encodes the T-cell receptor δ chain) and Clec7a (encodes C-type lectin domain family 7 member a, also known as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
