Article

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

2022-11-04

Abstract excerpt

<h4>SUMMARY</h4> Cancers often display immune escape, but the mechanisms and potential for reversibility are incompletely understood. Epigenetic dysregulation has been implicated in the immune escape of various cancer types. We have identified the epigenetic modifier SET and MYND-domain containing protein 3 (SMYD3) as a mediator of immune escape in human papilloma virus (HPV)- negative head and neck squamous cell...

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Literature Corpus work: 0353d14f-9269-556a-850d-c3f6d92b989f
DOI: 10.1101/2022.11.04.515098

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