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Effects of amyloid and <i>APOE4</i> on medial temporal lobe subregions in cognitively unimpaired elderly

2022-01-22

Abstract excerpt

Medial temporal lobe (MTL) sub-structures are differentially affected in early Alzheimer’s disease (AD), with a specific involvement of the entorhinal cortex (ERC), the perirhinal cortex (PRC) and CA1. However, the impact of amyloid (Aβ) pathology and APOE ε4 on MTL subregional atrophy remains relatively unknown. Our aim was to uncover these effects to further our understanding of the mechanisms underlying MTL atr...

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Literature Corpus work
034fdca1-e10a-57f9-8d04-6ed73845b66c
DOI
10.1101/2022.01.20.22269607
Open publication

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Effects of amyloid and <i>APOE4</i> on medial temporal lobe subregions in cognitively unimpaired elderlyDOI 10.1101/2022.01.20.22269607
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