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Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's disease

10 Dec 2018

Abstract excerpt

The most common presentation of early onset Alzheimer's disease (EOAD - defined as symptom onset <65 years) is with progressive episodic memory impairment - amnestic or typical Alzheimer's disease (tAD). However, EOAD is notable for its phenotypic heterogeneity, with posterior cortical atrophy (PCA) - characterised by prominent higher-order visual processing deficits and relative sparing of episodic memory - the...

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PMID: 30558867
DOI: 10.1016/j.nicl.2018.101632

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