Article

Unbalanced Sample Size Introduces Spurious Correlations to Genome-wide Heterozygosity Analyses

2020-02-07

Abstract excerpt

Excess of heterozygosity (H) is a widely used measure of genetic diversity of a population. As high-throughput sequencing and genotyping data become readily available, it has been applied to investigating the associations of genome-wide genetic diversity with human diseases and traits. However, these studies often report contradictory results. In this paper, we present a meta-analysis of five whole-exome studies t...

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Literature Corpus work: 03243741-fb4a-547b-a812-7f3d6b6a1cc0
DOI: 10.1101/2020.02.06.937599

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