Article

The distribution of deleterious genetic variation in human populations

2014-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Population genetic studies suggest that most amino-acid changing mutations are deleterious. Such mutations are of tremendous interest in human population genetics as they are important for the evolutionary process and may contribute risk to common disease. Genomic studies over the past 5 years have documented differences across populations in the number of heterozygous deleterious genotypes, num...

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Literature Corpus work: be1d4e35-ba77-56b0-ab3e-3f25ea8b1731
DOI: 10.1101/005330

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