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Article

Ascertainment bias and the pattern of nucleotide diversity at the human ALDH2 locus in a Japanese population.

Journal of molecular evolution - 1 Mar 2007

Brown Benjamin T, Woerner August, Wilder Jason A

Abstract excerpt

Many East Asian human populations harbor a high-frequency deficiency allele for the aldehyde dehydrogenase 2 (ALDH2) enzyme, a critical protein involved in the metabolism of ethanol. Here we use resequencing and long-range SNP haplotype data from a Japanese sample to test whether patterns of nucleotide diversity and linkage disequilibrium at this locus are compatible with a standard neutral model of evolution....

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Topics

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Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Linkage Disequilibrium

Share to Recombination, Genetic

Share to Selection, Genetic

Source

Identifiers

PMID: 17225965
DOI: 10.1007/s00239-006-0149-0

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ascertainment bias and the pattern of nucleotide diversity at the human ALDH2 locus in a Japanese population.PMID 17225965Read ↗

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