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Generation of red blood cells from induced pluripotent stem cells

13 Feb 2024

Abstract excerpt

PURPOSE OF REVIEW: Human induced pluripotent stem cells (iPSCs) are an attractive source to generate in-vitro-derived blood for use as transfusable and reagent red cells. We review recent advancements in the field and the remaining limitations for clinical use. RECENT FINDINGS: For iPSC-derived red blood cell (RBC) generation, recent work has optimized culture conditions to omit feeder cells, enhance red cell...

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PMID: 38362913
DOI: 10.1097/moh.0000000000000810

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