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Synthetic Receptors for Sensing Soluble Molecules with Mammalian Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Scheller Leo

Abstract excerpt

Synthetic receptors control cell behavior in response to environmental stimuli for applications in basic research and cell therapy. However, the integration of synthetic receptors in unexplored contexts is cumbersome, especially for nonspecialist laboratories. Here, I provide a detailed protocol on how to use receptors of the generalized extracellular molecule sensor (GEMS) platform. GEMS is a modular receptor...

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PMID: 34228282
DOI: 10.1007/978-1-0716-1441-9_2

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