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The average copy number variation (CNVA) of chromosome fragments is a potential surrogate marker for TMB in predicting responses to immunotherapy in Non-small cell lung cancer

2020-05-18

Abstract excerpt

<h4>Background: </h4> Genomic instability plays a large role in the process of cancer. Tumor mutational burden (TMB) is closely related to immunotherapy outcome and is an important manifestation of genomic instability. However, the cost of TMB detection is extremely high, which limits the use of TMB in clinical practice. Another new indicator of genome instability, CNVA (the average copy number variation) which ca...

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Literature Corpus work
5ba88153-86fe-5f17-8a93-115e09d3a213
DOI
10.21203/rs.3.rs-28650/v1
Open publication

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The average copy number variation (CNVA) of chromosome fragments is a potential surrogate marker for TMB in predicting responses to immunotherapy in Non-small cell lung cancerDOI 10.21203/rs.3.rs-28650/v1
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