Article

Intrahost evolution leading to distinct lineages in the upper and lower respiratory tracts during SARS-CoV-2 prolonged infection

2024-03-04

Abstract excerpt

Accumulating evidence points to persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in immunocompromised individuals as a source of genetically divergent, novel lineages, generally characterised by increased transmissibility and immune escape. While intrahost evolutionary dynamics of the virus in chronically infected patients have been previously reported, existing knowledge is prima...

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Literature Corpus work: 028dc0a9-191f-50b4-a54e-b1a1427d9f3f
DOI: 10.1101/2024.03.03.24303157

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