Article

Clonal dynamics after allogeneic haematopoietic cell transplantation using genome-wide somatic mutations

2023-04-28

Abstract excerpt

<title>Abstract</title> <p>Allogeneic haematopoietic cell transplantation (HCT) replaces the stem cells responsible for blood production with those harvested from a donor, and is received by 40,000 patients worldwide each year. To quantify dynamics of long-term stem cell engraftment, we sequenced whole genomes of 2,824 single-cell-derived haematopoietic colonies from blood samples of 10 donor-recipient pairs take...

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Literature Corpus work: 0248d079-49ad-5c8b-8f6d-259504a29694
DOI: 10.21203/rs.3.rs-2868644/v1

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