Article
The orofacial cleft risk gene IRF6 is a target gene of SOX9 in cranial neural crest cells
2025-10-20
Abstract excerpt
<title>Abstract</title> <p>Orofacial clefts represent the most prevalent congenital anomalies affecting the craniofacial region. They can be evoked by a disturbed development of either oral epithelium or cranial neural crest-derived mesenchyme, or by disruptions of their interplay. IRF6 is a well-known risk gene associated with orofacial clefts. Its expression in the oral epithelium depends on the transcription f...
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Identifiers and source
- Literature Corpus work
- 02288b0e-feff-56fc-89fe-749d4081b4be
- DOI
- 10.21203/rs.3.rs-7661291/v1