Article
A comprehensive consolidation of data on the relationship between IRF6 polymorphisms and non-syndromic cleft lip/palate susceptibility: From 79 case-control studies.
Journal of stomatology, oral and maxillofacial surgery - 1 Sept 2024
Golshan-Tafti Mohammad, Dastgheib Seyed Alireza, Bahrami Reza, Aarafi Hossein, Foroughi Elnaz, Mirjalili Seyed Reza, Kheirandish Naeimeh, Aghasipour Maryam, Shiri Amirmasoud, Azizi Sepideh, Aghili Kazem, Manzourolhojeh Mohammad, Neamatzadeh Hossein
Abstract excerpt
BACKGROUND: Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a prevalent craniofacial birth defect on a global scale. A number of candidate genes have been identified as having an impact on NSCL/P. However, the association between interferon regulatory factor 6 (IRF6) polymorphisms and NSCL/P has yielded inconsistent results, prompting the need for a meta-analysis to obtain more accurate...
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