Article
IRF6 polymorphisms are associated with nonsyndromic orofacial clefts in a Chinese Han population.
American journal of medical genetics. Part A - 1 Oct 2010
Pan Yongchu, Ma Junqing, Zhang Weibin, Du Yifei, Niu Yuming, Wang Meilin, Zhang Zhengdong, Wang Lin
Abstract excerpt
IRF6 plays an important role in orofacial development. In the present study, we genotyped two polymorphisms (rs642961 and rs2235371) within the IRF6 locus and estimated their associations with risk of nonsyndromic orofacial clefts (NSOC), including the subgroups, in a hospital-based case-control study in a Chinese Han population. In the single locus analyses, we found rs642961 AG and AG/AA genotypes were...
Topics
Join the communities discussing this publication.