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Article

A Novel Genetic Variation Identified in Patients With Orofacial Clefts.

The Journal of craniofacial surgery - 1 Jun 2025

Yu Li-Ling, Zeng Qi, Yu Bao-Fu, Wei Jiao, Dai Chuan-Chang

Abstract excerpt

BACKGROUND: Orofacial clefts represent the most prevalent form of craniomaxillofacial deformity. Genetic factors are particularly significant in the development of orofacial clefts. This study was to investigate genetic variation in patients with orofacial clefts. METHODS: This is a retrospective descriptive study. Whole-exome sequencing (WES) was conducted to identify mutated genes and mutation loci in patients...

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Cleft Lip
Cleft Palate
Exome Sequencing
Genetic Variation
Interferon Regulatory Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39679673
DOI: 10.1097/SCS.0000000000011011

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