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Requirement of <i>Irf6</i> and <i>Esrp1/2</i> in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish

2020-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Orofacial clefts are among the most common human congenital malformations. Irf6 and Esrp1 are two key genes important for palate development, conserved across vertebrates. In the zebrafish, we found that irf6 regulates the expression of esrp1 . Using RNAscope, we detailed overlapping Irf6 and Esrp1/2 gene expression in the mouse frontonasal prominence ectoderm, lambda joint periderm, palate...

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Literature Corpus work
bed0e2e8-60a0-5733-80eb-0b8d70958fa5
DOI
10.1101/2020.06.14.149773
Open publication

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Requirement of <i>Irf6</i> and <i>Esrp1/2</i> in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafishDOI 10.1101/2020.06.14.149773
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