Article

A History and Atlas of the Human CD4+ T Helper Cell

2023-07-31

Abstract excerpt

CD4+ T cells orchestrate and regulate immunity within jawed vertebrates, yet our understanding of their evolution, development, and cellular physiology has only begun to be unearthed in the past few decades. Discoveries of genetic diseases that ablate this cellular population have provided insight into their critical functions while transcriptomics, proteomics, and highresolution microscopy have recently revealed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 01f851f5-9250-5747-b3ad-a0f05bf56efc
DOI: 10.20944/preprints202307.2055.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A History and Atlas of the Human CD4+ T Helper CellDOI 10.20944/preprints202307.2055.v1Read

T cells in health and diseaseSemantic proximity Read

Single-cell analysis to understand the diversity of immune cell types that drive disease pathogenesisSemantic proximity Read

Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cellsSemantic proximity Read

The human T‐cell receptor repertoire in health and disease and potential for omics integrationSemantic proximity Read

Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cellsSemantic proximity Read

A unified atlas of CD8 T cell dysfunctional states in cancer and infectionSemantic proximity Read

Unraveling the Phenotypic States of Human innate-like T Cells: Comparative Insights with Conventional T Cells and Mouse ModelsSemantic proximity Read

Multi-organ single-cell transcriptomics of immune cells uncovered organ-specific gene expression and functionsSemantic proximity Read

CD4 T cells: fates, functions, and faults.Semantic proximity Read

Legend or Truth: Mature CD4+CD8+ Double-Positive T Cells in the Periphery in Health and DiseaseSemantic proximity Read

Unraveling the secrets of γδ T cells with single-cell biologySemantic proximity Read

Reproducible single cell annotation of programs underlying T-cell subsets, activation states, and functionsSemantic proximity Read