Article

Evolution under vancomycin selection drives divergent collateral sensitivity patterns in <i>Staphylococcus aureus</i>

2023-12-01

Abstract excerpt

Staphylococcus aureus bacteremia is typically treated empirically with vancomycin, with therapy later tailored based on susceptibility results. However, these tests occur before vancomycin exposure and do not account for adaptation during empiric treatment that can alter S. aureus ’ susceptibility to first-line drugs. To investigate these collateral drug responses, we experimentally evolved 18 methicillin-suscept...

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Literature Corpus work: 01e0c89e-aba9-56c3-864c-60cadce01d53
DOI: 10.1101/2023.11.30.569373

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