Article

The impact of immunosuppression on nucleotide sequence diversity in the first hypervariable region (HVR1) of hepatitis C virus (HCV)

1997-01-01

Abstract excerpt

Hepatitis C virus (HCV) is responsible for most cases of non-A, non-B hepatitis. The persistent nature of this virus has been attributed to viral replication errors, which lead to a dynamic pool of antigenic variants that allow escape from the host immune response. A major part of this escape is due to the hypervariable region 1 (HVR1) of HCV, known to encode structurally flexible, isolate-specific neutralising ep...

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Literature Corpus work: 01cd478d-ba3d-5e0d-86ea-e983dd3a5d07
DOI: 10.21954/ou.ro.0000f5db

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