Article
Hepatitis C virus genomic variability in untreated and immunosuppressed patients.
Virology - 3 Feb 1997
Lawal Z, Petrik J, Wong V S, Alexander G J, Allain J P
Abstract excerpt
To investigate whether immune pressure enhances the genetic diversity of the hepatitis C virus (HCV) hypervariable region 1, nucleotide sequences were compared in multiple sera, collected longitudinally, from three untreated patients and four patients undergoing liver transplantation for HCV-related cirrhosis. A minor variant became dominant in three of three patients following transplantation and persisted...
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