Article
Common variation in meiosis genes shapes human recombination phenotypes and aneuploidy risk
2025-04-04
Abstract excerpt
The leading cause of human pregnancy loss is aneuploidy, often tracing to errors in chromosome segregation during female meiosis. While abnormal crossover recombination is known to confer risk for aneuploidy, limited data have hindered understanding of the potential shared genetic basis of these key molecular phenotypes. To address this gap, we performed retrospective analysis of preimplantation genetic testing da...
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Identifiers and source
- Literature Corpus work
- 01b3adce-ef06-5c0d-bef2-449111455412
- DOI
- 10.1101/2025.04.02.25325097