Article
Genome-Wide Association Study of Meiotic Recombination Phenotypes.
G3 (Bethesda, Md.) - 7 Dec 2016
Begum Ferdouse, Chowdhury Reshmi, Cheung Vivian G, Sherman Stephanie L, Feingold Eleanor
Abstract excerpt
Meiotic recombination is an essential step in gametogenesis, and is one that also generates genetic diversity. Genome-wide association studies (GWAS) and molecular studies have identified genes that influence of human meiotic recombination. RNF212 is associated with total or average number of recombination events, and PRDM9 is associated with the locations of hotspots, or sequences where crossing over appears to...
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