Article

Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos

2023-06-09

Abstract excerpt

Meiotic recombination is crucial for human genetic diversity and chromosome segregation accuracy. Understanding its variation across individuals and the processes by which it goes awry are long-standing goals in human genetics. Current approaches for inferring recombination landscapes either rely on population genetic patterns of linkage disequilibrium (LD)—capturing a time-averaged view—or direct detection of cro...

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Literature Corpus work: f422ddac-6b1c-5f09-ab93-525308bf1448
DOI: 10.1101/2023.06.07.543910

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