Article

Whole-Genome analyses of 1,364 breast cancers with clinical records

2024-09-30

Abstract excerpt

<title>Abstract</title> <p>Recent advancements in genomic technologies have become critical tools for deciphering the genetic complexities of cancer tissues, enabling precision medicine strategies aimed at improving patient clinical outcomes. Here we performed a comprehensive analysis of clinically annotated whole genome and whole transcriptome sequences from 1,364 breast cancer cases. Our investigation provides...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 019b0365-8dc8-5524-886b-bdf9fafc027f
DOI: 10.21203/rs.3.rs-5094752/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-Genome analyses of 1,364 breast cancers with clinical recordsDOI 10.21203/rs.3.rs-5094752/v1Read

Whole-genome landscapes of 1,364 breast cancers.Semantic proximity Read

Complex rearrangements fuel ER+ and HER2+ breast tumoursSemantic proximity Read

Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancerSemantic proximity Read

Frequent Whole-Genome Duplication Events Drive the Genomic Evolution of Triple-Negative Breast Cancer During Neoadjuvant ChemotherapySemantic proximity Read

Whole genome sequencing of locally advanced and metastatic breast carcinoma unravels relevant molecular signatures and novel events.Semantic proximity Read

Breast Cancer: A Molecularly Heterogenous Disease Needing Subtype-Specific TreatmentsSemantic proximity Read

Frequent Whole-Genome Duplication Events Drive the Genomic Evolution of Triple-Negative Breast Cancer During Neoadjuvant ChemotherapySemantic proximity Read

The Cancer Genome Atlas: clinical applications for breast cancer.Semantic proximity Read

Clinical potential of whole-genome data linked to mortality statistics in patients with breast cancer in the UK: a retrospective analysis.Semantic proximity Read

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization.Semantic proximity Read

Determination of Copy Number Variations and Affected Gene Networks in Breast Cancer from Mexican PatientsSemantic proximity Read

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers.Semantic proximity Read