Article

Zinc Metabolic Defect of Aging Alveolar Progenitors in Progressive Pulmonary Fibrosis

2020-07-30

Abstract excerpt

<h4>SUMMARY</h4> Idiopathic pulmonary fibrosis (IPF) is a fatal form of interstitial lung disease and aging has been identified as a risk factor to the disease. Alveolar type II cells (AEC2s) function as progenitor cells in the lung. Growing evidences indicate that IPF results from repeating AEC2 injury and inadequate epithelial repair. We previously reported that there was a significant loss of alveolar progenit...

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Literature Corpus work: 0151e3d4-727c-5107-9d74-0bd8f712bdd8
DOI: 10.1101/2020.07.30.229567

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