Article

Transient receptor potential vanilloid channel 2 contributes to multi-modal endoplasmic reticulum and perinuclear space dilations that can also be observed in prion-infected mice

2024-12-20

Abstract excerpt

<h4>ABSTRACT</h4> Our recent work on the prion protein and Na + ,K + -ATPases (NKAs) led us to revisit data from over 50 years ago, which suggested a similarity between vacuolation phenotypes in rodents poisoned with cardiac glycosides (CGs) and spongiform degeneration in prion disease. At that time, this hypothesis was dismissed because the vacuolation observed in prion diseases affects neurons, whereas CG poi...

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Literature Corpus work: 0032e5d3-7709-539d-92ba-ef7fac0f06da
DOI: 10.1101/2024.12.18.629254

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Transient receptor potential vanilloid channel 2 contributes to multi-modal endoplasmic reticulum and perinuclear space dilations that can also be observed in prion-infected miceDOI 10.1101/2024.12.18.629254Read

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