Article
Abnormal intracellular ca(2+)homeostasis and disease.
Cell calcium - 1 Jul 2000
Missiaen L, Robberecht W, van den Bosch L, Callewaert G, Parys J B, Wuytack F, Raeymaekers L, Nilius B, Eggermont J, De Smedt H
Abstract excerpt
A whole range of cell functions are regulated by the free cytosolic Ca(2+)concentration. Activator Ca(2+)from the extracellular space enters the cell through various types of Ca(2+)channels and sometimes the Na(+)/Ca(2+)-exchanger, and is actively extruded from the cell by Ca(2+)pumps and Na(+)/Ca(2+)-exchangers. Activator Ca(2+)can also be released from internal Ca(2+)stores through inositol trisphosphate or...
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