Article
Activity-dependent endoplasmic reticulum Ca <sup>2+</sup> uptake depends on Kv2.1-mediated endoplasmic reticulum/plasma membrane junctions to promote synaptic transmission
2021-10-23
Abstract excerpt
The endoplasmic reticulum (ER) forms a continuous and dynamic network throughout a neuron, extending from dendrites to axon terminals, and axonal ER dysfunction is implicated in several neurological disorders. In addition, tight junctions between the ER and plasma membrane (PM) are formed by several molecules including Kv2 channels, but the cellular functions of many ER-PM junctions remain unknown. Dynamic Ca 2+...
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Identifiers and source
- Literature Corpus work
- 14c10201-0c4b-57a1-a541-96ae4d45b885
- DOI
- 10.1101/2021.10.23.465516
