Article

Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platforms

2024-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Cardiovascular disease stands as the leading cause of death globally, claiming approximately 19million lives in 2020. On the contrary, the development of cardiovascular drugs is experiencing a decline, largely due to the bottleneck in understanding the pathophysiology of various heart diseases and assessing the effects of drugs on healthy human hearts. The development of induced pluripotent stem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0005c485-a7fe-5821-bc64-3bbc9a4c7e5d
DOI: 10.1101/2024.12.04.626684

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platformsDOI 10.1101/2024.12.04.626684Read

Progressive developmental cues from multiple cardiac cell types promote cardiomyocyte maturationSemantic proximity Read

Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac MyocytesSemantic proximity Read

Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathySemantic proximity Read

Mitochondria Clearance Enables Macrophage-Driven Maturation of iPSC-Derived Cardiomyocyte MetabolismSemantic proximity Read

Cardiomyocyte Maturation-the Road is not Obstructed.Semantic proximity Read

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart DiseaseSemantic proximity Read

Metabolically-Driven Maturation of hiPSC-Cell Derived Cardiac ChipSemantic proximity Read

Dynamic Electrical Stimulation Promotes hiPSC-CM Differentiation and FunctionalitySemantic proximity Read

Making human cardiomyocytes up to date: Derivation, maturation state and perspectivesSemantic proximity Read

Enhanced iPSC Cardiomyocyte Maturation via Combined 3D-Culture and Metabolic CuesSemantic proximity Read

Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic CardiomyopathySemantic proximity Read

Comprehensive promotion of iPSC-CM maturation by integrating metabolic medium, nanopatterning, and electrostimulationSemantic proximity Read